Medication Kills Thousands Annualy

Wrong Amounts = Early Grave.

Please READ your prescription labels very carefully. Getting the wrong drug or the wrong dosage does kill hundreds or thousands of people each year, with many times that number getting injured.  Renegade health reporter Nicholas Regush — a self-imposed exile from ABC News — provides long list of specific problems:

Poor handwriting. Verbal orders. Ambiguous orders. Prescribing errors.  Failure to write orders. Unapproved uses. When the order is not modified or cancelled. Look-alike and sound-alike drug names. Dangerous abbreviations. Faulty drug distribution systems in hospital. Failure to read the label or poor labeling. Lack of knowledge about drugs. Lack of knowledge concerning proper dose. Lack of knowledge concerning route of administration. Nauseam.

After pouring over death certificates, sociology professor David Philips — an expert in mortalitystatistics — determined that drug errors kill 7,000 people each year in the US. His study was Institute of Medicine, a branch of the National Academies of Science, also estimated 7,000.  Interestingly, the Food and Drug Administration published the lowball figure of 365 annually (one per day). But even the FDA admits that such bungling injures 1.3 million people each year.  New York Newsday cited several specific cases, such as: “In 1995, a Texas doctor wrote an illegible prescription causing the patient to receive not only the wrong medication, but at eight times the drug’s usually recommended strength. The patient, Ramon Vasquez, died. In 1999, a court ordered the doctor and pharmacy to  pay the patient’s family a total of $450,000, the largest amount ever awarded in an illegible prescription case.”

Besides doctors’ indecipherable chicken scratch, similar-sounding drug names are another big culprit. Pharmaceutical companies have even started warning medical professionals to be careful with the cookie-cutter names of their products. In a typical example, Celebrex, Cerebyx, Celexa, and Zyprexa sometimes get confused. (Respectively, they’re used to treat arthritis, seizures, depression, and psychosis.) According to WebMD: “Bruce Lambert, an assistant professor of pharmacy administration at the University of Illinois at Chicago, says there are 100,000 potential pairings of drug names that could be confused.”

Any Amount can = Early Grave!

Even higher than the number of people who die from medication errors is the number of people who die from medication, period. Even when a prescription drug is dispensed properly, there’s no guarantee it won’t end up killing you.

A remarkable study in the Journal of the American Medical Association revealed that prescription drugs kill around 106,000 people in the US every year, which ranks prescription drugs as the fourth leading cause of death. Furthermore, each years sees 2,216,000 serious adverse drug reactions (defined as “those that required hospitalization, were permanently disabling, or resulted in death”).  The authors of this 1998 study performed a meta-analysis on 39 previous studies covering 32 years. They factored out such things as medication errors, abuse of prescription drugs, and adverse reactions not considered serious. Plus, the study involved only people who had either been hospitalized due to drug reactions or who experienced reactions while in the hospital. People who died immediately (and, thus, never went to the hospital) and those whose deaths weren’t realized to be due to prescription drugs were not included, so the true figure is probably higher.  Four years later, another study in the JAMA warned:

Patient exposure to new drugs with unknown toxic effects may be extensive. Nearly 20 million patients in the United States took at least 1 of the 5 drugs withdrawn from the market between September 1997 and September 1998. Three of these 5 drugs were new, having been on the market for less than 2 years. Seven drugs approved since 1993 and subsequently withdrawn from the market have been reported as possibly contributing to 1002 deaths.

Examining warnings added to drug labels through the years, the study’s authors found that of the new chemical entities approved from 1975 to 1999, 10 percent “acquired a new black box warning or were withdrawn from the market” by 2000. Using some kind of high-falutin’ statistical process, they estimate that the “probability of a new drug acquiring black box warnings or being withdrawn from the market over 25 years was 20%.”  A statement released by one of the study’s coauthors — Sidney Wolfe, MD, Director of Public Citizen’s Health Studies Group — warned:

In 1997, 39 new drugs were approved by the FDA. As of now [May 2002], five of them (Rezulin, Posicor, Duract, Raxar and Baycol) have been taken off the market and an additional two (Trovan, an antibiotic and Orgaran, an anticoagulant) have had new box warnings. Thus, seven drugs approved that year (18% of the 39 drugs approved) have already been withdrawn or had a black box warning in just four years after approval.  Based on our study, 20% of drugs will be withdrawn or have a black box warning within 25 years of coming on the market. The drugs approved in 1997 have already almost “achieved” this in only four years — with 21 years to go.

How does this happen? Before the FDA approves a new drug, it must undergo clinical trials.  These trials aren’t performed by the FDA, though — they’re done by the drug companies themselves. These trials often use relatively few patients, and they usually select patients most likely to react well to the drug. On top of that, the trials are often for a short period of time (weeks), even though real-world users may be on a drug for months or years at a time.

Dr. Wolfe points out that even when adverse effects show up during clinical trials, the drugs are sometimes released anyway, and they end up being taken off the market because of those same adverse effects.  Post marketing reporting of adverse effects isn’t much better. The FDA runs a program to collect reports of problems with drugs, but compliance is voluntary. The generally accepted estimate in the medical community is that a scant 10 percent of individual instances of adverse effects are reported to the FDA, which would mean that the problem is ten times worse than we currently believe.

Drugs aren’t released when they’ve been proven safe; they’re released when enough FDA bureaucrats — many of whom have worked for the pharmaceutical companies or will work for them in the future — can be convinced that it’s kinda safe. Basically, the use of prescription drugs by the general public can be seen as widespread, long-term clinical trials to determine their true safety.  We are all guinea pigs.

References:

http://12tips.blogspot.com/2010/12/medication-errors-kill-thousands-each.html

http://www.tgdaily.com/general-sciences-features/43559-medical-errors-kill-thousands-each-year

http://www.leweschiro.com/mederror.html

Russ Kick
Published by The Disinformation Company Ltd.

This entry was posted in Uncategorized. Bookmark the permalink.

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  286. Hey! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good results. If you know of any please share. Cheers!

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  289. Greetings! I know this is somewhat off topic but I was wondering if you knew where I could locate a captcha plugin for my comment form? I’m using the same blog platform as yours and I’m having difficulty finding one? Thanks a lot!

  290. Currently it appears like Expression Engine is the best blogging platform out there right now. (from what I’ve read) Is that what you’re using on your blog?

  291. Hello there! This is kind of off topic but I need some help from an established blog. Is it difficult to set up your own blog? I’m not very techincal but I can figure things out pretty fast. I’m thinking about creating my own but I’m not sure where to start. Do you have any ideas or suggestions? Cheers

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  294. Right now it sounds like Movable Type is the top blogging platform out there right now. (from what I’ve read) Is that what you are using on your blog?

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  296. When I originally commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get three e-mails with the same comment. Is there any way you can remove people from that service? Many thanks!

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  309. Howdy! I know this is sort of off-topic but I needed to ask. Does managing a well-established blog such as yours take a lot of work? I am brand new to blogging but I do write in my diary daily. I’d like to start a blog so I can easily share my experience and views online. Please let me know if you have any ideas or tips for new aspiring bloggers. Thankyou!

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  314. Hi! I know this is kinda off topic however , I’d figured I’d ask. Would you be interested in trading links or maybe guest writing a blog post or vice-versa? My website addresses a lot of the same topics as yours and I believe we could greatly benefit from each other. If you are interested feel free to shoot me an e-mail. I look forward to hearing from you! Great blog by the way!

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  317. Hey! This is kind of off topic but I need some guidance from an established blog. Is it hard to set up your own blog? I’m not very techincal but I can figure things out pretty quick. I’m thinking about making my own but I’m not sure where to start. Do you have any points or suggestions? Many thanks

  318. I do not know whether it’s just me or if perhaps everybody else experiencing issues with your website. It seems like some of the written text on your posts are running off the screen. Can someone else please comment and let me know if this is happening to them too? This could be a issue with my internet browser because I’ve had this happen previously. Kudos

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  320. Currently it appears like Expression Engine is the preferred blogging platform out there right now. (from what I’ve read) Is that what you’re using on your blog?

  321. First of all I would like to say excellent blog! I had a quick question in which I’d like to ask if you do not mind. I was curious to know how you center yourself and clear your head before writing. I have had a tough time clearing my mind in getting my ideas out. I do enjoy writing however it just seems like the first 10 to 15 minutes are generally wasted just trying to figure out how to begin. Any recommendations or hints? Thanks!

  322. Hi there this is kind of of off topic but I was wanting to know if blogs use WYSIWYG editors or if you have to manually code with HTML. I’m starting a blog soon but have no coding experience so I wanted to get advice from someone with experience. Any help would be enormously appreciated!

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  325. First off I would like to say excellent blog! I had a quick question that I’d like to ask if you don’t mind. I was interested to know how you center yourself and clear your head prior to writing. I have had trouble clearing my thoughts in getting my ideas out there. I truly do enjoy writing but it just seems like the first 10 to 15 minutes are wasted just trying to figure out how to begin. Any ideas or tips? Thank you!

  326. Hmm is anyone else having problems with the images on this blog loading? I’m trying to figure out if its a problem on my end or if it’s the blog. Any responses would be greatly appreciated.

  327. My programmer is trying to convince me to move to .net from PHP. I have always disliked the idea because of the costs. But he’s tryiong none the less. I’ve been using Movable-type on a number of websites for about a year and am anxious about switching to another platform. I have heard fantastic things about blogengine.net. Is there a way I can transfer all my wordpress posts into it? Any kind of help would be greatly appreciated!

  328. Hey I know this is off topic but I was wondering if you knew of any widgets I could add to my blog that automatically tweet my newest twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would have some experience with something like this. Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.

  329. Wow that was unusual. I just wrote an very long comment but after I clicked submit my comment didn’t appear. Grrrr… well I’m not writing all that over again. Anyway, just wanted to say fantastic blog!

  330. I know this if off topic but I’m looking into starting my own blog and was wondering what all is needed to get set up? I’m assuming having a blog like yours would cost a pretty penny? I’m not very web savvy so I’m not 100% positive. Any suggestions or advice would be greatly appreciated. Many thanks

  331. Hi! Do you know if they make any plugins to assist with SEO? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good success. If you know of any please share. Appreciate it!

  332. When I originally commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get four emails with the same comment. Is there any way you can remove people from that service? Thanks!

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  337. Hmm is anyone else having problems with the images on this blog loading? I’m trying to determine if its a problem on my end or if it’s the blog. Any suggestions would be greatly appreciated.

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  346. I know this if off topic but I’m looking into starting my own blog and was wondering what all is needed to get setup? I’m assuming having a blog like yours would cost a pretty penny? I’m not very internet smart so I’m not 100% certain. Any tips or advice would be greatly appreciated. Many thanks

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  351. Hello would you mind stating which blog platform you’re using? I’m planning to start my own blog in the near future but I’m having a hard time deciding between BlogEngine/Wordpress/B2evolution and Drupal. The reason I ask is because your layout seems different then most blogs and I’m looking for something completely unique. P.S Sorry for getting off-topic but I had to ask!

  352. Fantastic blog! Do you have any suggestions for aspiring writers? I’m hoping to start my own website soon but I’m a little lost on everything. Would you advise starting with a free platform like WordPress or go for a paid option? There are so many options out there that I’m completely confused .. Any recommendations? Appreciate it!

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  361. Hello there! This is kind of off topic but I need some advice from an established blog. Is it very hard to set up your own blog? I’m not very techincal but I can figure things out pretty quick. I’m thinking about making my own but I’m not sure where to start. Do you have any tips or suggestions? With thanks

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